SnapShot: GPCR-Ligand Interactions
نویسندگان
چکیده
G-protein-coupled receptors enable cells to recognize numerous external stimuli and to transmit corresponding signals across the plasma membrane to trigger appropriate cellular responses. Crystal structures of a number of these receptors have now been determined in inactive and active conformations bound to chemically and functionally distinct ligands. These crystal structures illustrate overall receptor organization and atomic details of ligand-receptor interactions.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 159 شماره
صفحات -
تاریخ انتشار 2014